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Table 20: Etiological Causes of Delayed Ejaculation and Anejaculation [852]

                        Ageing Men                   Degeneration of penile afferent nerves inhibited ejaculation
                        Congenital                   Mullerian duct cyst
                                                     Wolfian duct abnormalities
                                                     Prune Belly Syndrome
                                                     Imperforate Anus
                                                     Genetic abnormalities
                        Anatomic causes              Transurethral resection of prostate
                                                     Bladder neck incision
                                                     Circumcision
                                                     Ejaculatory duct obstruction (can be congenital or acquired)
                        Neurogenic causes            Diabetic autonomic neuropathy
                                                     Multiple sclerosis
                                                     Spinal cord injury
                                                     Radical prostatectomy
                                                     Proctocolectomy
                                                     Bilateral sympathectomy
                                                     Abdominal aortic aneurysmectomy
                                                     Para-aortic lymphadenectomy
                        Infective/Inflammation       Urethritis
                                                     Genitourinary tuberculosis
                                                     Schistosomiasis
                                                     Prostatitis
                                                     Orchitis
                        Endocrine                    Hypogonadism
                                                     Hypothyroidism
                                                     Prolactin disorders
                        Medication                   Antihypertensives; thiazide diuretics
                                                     Alpha-adrenergic blockers
                                                     Antipsychotics and antidepressants
                                                     Alcohol
                                                     Antiandrogens
                                                     Ganglion blockers
                                                     Selective serotonin reuptake Inhibitors
                        Psychological                Acute psychological distress
                                                     Relationship distress
                                                     Psychosexual skill deficit
                                                     Disconnect between arousal and sexual situations
                                                     Masturbation style


                        6.3.3   Investigation and treatment
                        Patients should have a full medical and sexual history performed along with a detailed physical examination
                        when evaluating for DE. It is not uncommon for clinicians to feel uncomfortable with the level of sexual
                        information that is warranted in obtaining a full sexual history. Understanding the details of the ejaculatory
                        response, sensation, frequency, and sexual activity/techniques; cultural context and history of the disorder;
                        quality of the sexual response cycle (desire, arousal, ejaculation, orgasm, and refractory period); partner’s
                        assessment of the disorder and if the partner suffers from any sexual dysfunction her/himself; and the overall
                        satisfaction of the sexual relationship are all important to garner during history-taking [853]. Investigation by
                        a sex therapist is often required to help obtain a complete psychological evaluation. It is incumbent on the
                        clinician to diagnose medical pathologies that cause or contribute to DE, such as assessing the hormonal
                        milieu, anatomy, and overall medical condition. Good communication between the sex therapist and medical
                        practitioner is vital to successful diagnosis and treatment of DE.

                        6.3.3.1   Psychological aspects and intervention
                        There is scarce literature on the psychological aspects relating to DE, as well as on empirical evidence
                        regarding psychological treatment efficacy. Studies on psychological aspects have revealed that men with
                        DE show a strong need to control their sexual experiences. Delayed ejaculation is associated with difficulties
                        surrendering to sexual pleasure during sex - i.e., the sense of letting go [854] - which denotes a psychological




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